POLES OF THE MERIDAIN

\pˈə͡ʊlz ɒvðə mˌɛɹɪdˈe͡ɪn], \pˈə‍ʊlz ɒvðə mˌɛɹɪdˈe‍ɪn], \p_ˈəʊ_l_z ɒ_v_ð_ə m_ˌɛ_ɹ_ɪ_d_ˈeɪ_n]\

Definitions of POLES OF THE MERIDAIN

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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