POLES OF THE HORIZON

\pˈə͡ʊlz ɒvðə həɹˈa͡ɪzən], \pˈə‍ʊlz ɒvðə həɹˈa‍ɪzən], \p_ˈəʊ_l_z ɒ_v_ð_ə h_ə_ɹ_ˈaɪ_z_ə_n]\

Definitions of POLES OF THE HORIZON

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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