ISCHIATIC REGION

\ˌɪskɪˈatɪk ɹˈiːd͡ʒən], \ˌɪskɪˈatɪk ɹˈiːd‍ʒən], \ˌɪ_s_k_ɪ__ˈa_t_ɪ_k ɹ_ˈiː_dʒ_ə_n]\
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1846 - Medical lexicon: a dictionary of medical science
By Robley Dunglison

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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