FILIPOWICZ'S SYMPTOM

\fˈɪlɪpˌa͡ʊɪkzɪz sˈɪmptəm], \fˈɪlɪpˌa‍ʊɪkzɪz sˈɪmptəm], \f_ˈɪ_l_ɪ_p_ˌaʊ_ɪ_k_z_ɪ_z s_ˈɪ_m_p_t_ə_m]\

Definitions of FILIPOWICZ'S SYMPTOM

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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