FILIPOVITCH'S SIGN

\fɪlˈɪpəvˌɪt͡ʃɪz sˈa͡ɪn], \fɪlˈɪpəvˌɪt‍ʃɪz sˈa‍ɪn], \f_ɪ_l_ˈɪ_p_ə_v_ˌɪ_tʃ_ɪ_z s_ˈaɪ_n]\

Definitions of FILIPOVITCH'S SIGN

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1898 - American pocket medical dictionary
By Willam Alexander Newman Dorland

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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