VON WILLEBRAND DISEASE
\vˈɒn wˈɪlɪbɹˌand dɪzˈiːz], \vˈɒn wˈɪlɪbɹˌand dɪzˈiːz], \v_ˈɒ_n w_ˈɪ_l_ɪ_b_ɹ_ˌa_n_d d_ɪ_z_ˈiː_z]\
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Group of hemorrhagic disorders in which the von Willebrand factor (Factor VIII-related antigen) is either quantitatively or qualitatively abnormal. They are usually inherited as an autosomal dominant trait though rare kindreds are autosomal recessive. Symptoms vary depending on severity and disease type but may include prolonged bleeding time, deficiency of factor VIII, and impaired platelet adhesion.
By DataStellar Co., Ltd
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