UNSUBDUED
\ʌnsʌbdjˈuːd], \ʌnsʌbdjˈuːd], \ʌ_n_s_ʌ_b_d_j_ˈuː_d]\
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Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.