TRANSKETOLASE
\tɹanskˈɛtəlˌe͡ɪs], \tɹanskˈɛtəlˌeɪs], \t_ɹ_a_n_s_k_ˈɛ_t_ə_l_ˌeɪ_s]\
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An enzyme of the transferase class that catalyzes the conversion of sedoheptulose 7-phosphate and D-glyceraldehyde 3-phosphate to D-ribose 5-phosphate and D-xylulose 5-phosphate in the pentosephosphate pathway. (Dorland, 27th ed) EC 2.2.1.1.
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Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.