RUFUS CHOATE
\ɹˈuːfəs t͡ʃˈə͡ʊt], \ɹˈuːfəs tʃˈəʊt], \ɹ_ˈuː_f_ə_s tʃ_ˈəʊ_t]\
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A famous American lawyer, orator and statesman; born at Essex, Mass., Oct. 1, 1799; died at Halifax, N. S., July 13, 1859. He succeeded Daniel Webster in the United States Senate (1841-45), and was long the acknowledged leader of the Massachusetts bar. He was one of the most distinguished of American orators. His works were published in 1863 (2 vols.).
By Charles Dudley Warner
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Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.