PIETRO GIANNONE

\pˈa͡ɪ͡ətɹə͡ʊ d͡ʒɐnˈɒn], \pˈa‍ɪ‍ətɹə‍ʊ d‍ʒɐnˈɒn], \p_ˈaɪə_t_ɹ_əʊ dʒ_ɐ_n_ˈɒ_n]\
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1910 - Warner's dictionary of authors ancient and modern
By Charles Dudley Warner

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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