IMPROV(V)ISATORE
\ɪmpɹˈɒv vˈiː ˈɪsatə], \ɪmpɹˈɒv vˈiː ˈɪsatə], \ɪ_m_p_ɹ_ˈɒ_v__ v_ˈiː__ ˈɪ_s_a_t_ə]\
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Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.