EQUILIBRIUM LAW

\ˌiːkwɪlˈɪbɹi͡əm lˈɔː], \ˌiːkwɪlˈɪbɹi‍əm lˈɔː], \ˌiː_k_w_ɪ_l_ˈɪ_b_ɹ_iə_m l_ˈɔː]\
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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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