DIFFERENTIATION REVERSAL FACTOR

\dˌɪfəɹˌɛnʃɪˈe͡ɪʃən ɹɪvˈɜːsə͡l fˈaktə], \dˌɪfəɹˌɛnʃɪˈe‍ɪʃən ɹɪvˈɜːsə‍l fˈaktə], \d_ˌɪ_f_ə_ɹ_ˌɛ_n_ʃ_ɪ__ˈeɪ_ʃ_ə_n ɹ_ɪ_v_ˈɜː_s_əl f_ˈa_k_t_ə]\

Definitions of DIFFERENTIATION REVERSAL FACTOR

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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