DESIGNER DRUGS
\dɪzˈa͡ɪnə dɹˈʌɡz], \dɪzˈaɪnə dɹˈʌɡz], \d_ɪ_z_ˈaɪ_n_ə d_ɹ_ˈʌ_ɡ_z]\
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Drugs designed and synthesized, often for illegal street use, by modification of existing drug structures (e.g., amphetamines). Of special interest are MPTP (a reverse ester of meperidine), MDA (3,4-methylenedioxyamphetamine), and MDMA (3,4-methylenedioxymethamphetamine). Many drugs act on the aminergic system, the physiologically active biogenic amines.
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Word of the day
Dopamine Acetyltransferase
- An enzyme that catalyzes the of groups from acetyl-CoA to arylamines. They have wide specificity for aromatic amines, particularly serotonin, and can also catalyze acetyl transfer between arylamines without CoA. EC 2.3.1.5.