CONSTITUTIONAL CAUSE
\kˌɒnstɪtjˈuːʃənə͡l kˈɔːz], \kˌɒnstɪtjˈuːʃənəl kˈɔːz], \k_ˌɒ_n_s_t_ɪ_t_j_ˈuː_ʃ_ə_n_əl k_ˈɔː_z]\
Definitions of CONSTITUTIONAL CAUSE
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Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.