BELL AND LANCASTER SYSTEM
\bˈɛl and lˈankastə sˈɪstəm], \bˈɛl and lˈankastə sˈɪstəm], \b_ˈɛ_l a_n_d l_ˈa_n_k_a_s_t_ə s_ˈɪ_s_t_ə_m]\
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Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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