BACKBREAKING
\bˈakbɹe͡ɪkɪŋ], \bˈakbɹeɪkɪŋ], \b_ˈa_k_b_ɹ_eɪ_k_ɪ_ŋ]\
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characterized by toilsome effort to the point of exhaustion; especially physical effort; "worked their arduous way up the mining valley"; "a grueling campaign"; "hard labor"; "heavy work"; "heavy going"; "spent many laborious hours on the project"; "set a punishing pace"
By Princeton University
Word of the day
Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.