VON WILLEBRANDS DISEASE
\vˈɒn wˈɪlɪbɹˌandz dɪzˈiːz], \vˈɒn wˈɪlɪbɹˌandz dɪzˈiːz], \v_ˈɒ_n w_ˈɪ_l_ɪ_b_ɹ_ˌa_n_d_z d_ɪ_z_ˈiː_z]\
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Group of hemorrhagic disorders in which the von Willebrand factor (Factor VIII-related antigen) is either quantitatively or qualitatively abnormal. They are usually inherited as an autosomal dominant trait though rare kindreds are autosomal recessive. Symptoms vary depending on severity and disease type but may include prolonged bleeding time, deficiency of factor VIII, and impaired platelet adhesion.
By DataStellar Co., Ltd
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