TRANSLOCATION (GENETICS)
\tɹanslə͡ʊkˈe͡ɪʃən d͡ʒɛnˈɛtɪks], \tɹansləʊkˈeɪʃən dʒɛnˈɛtɪks], \t_ɹ_a_n_s_l_əʊ_k_ˈeɪ_ʃ_ə_n__ dʒ_ɛ_n_ˈɛ_t_ɪ_k_s]\
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A type of aberration characterized by fragmentation of a chromosome and transfer of the broken-off portion to another chromosome, often of a different pair.
By DataStellar Co., Ltd
Word of the day
Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.