TAP OUT
\tˈap ˈa͡ʊt], \tˈap ˈaʊt], \t_ˈa_p ˈaʊ_t]\
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Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.