PI 3K ISOTYPE P110 GAMMA
\pˌiːˈa͡ɪ θɹˈiː kˈe͡ɪ ˈa͡ɪsətˌa͡ɪp pˈiː wˈɒnhˈʌndɹədən tˈɛn ɡˈamə], \pˌiːˈaɪ θɹˈiː kˈeɪ ˈaɪsətˌaɪp pˈiː wˈɒnhˈʌndɹədən tˈɛn ɡˈamə], \p_ˌiː__ˈaɪ θ_ɹ_ˈiː k_ˈeɪ ˈaɪ_s_ə_t_ˌaɪ_p p_ˈiː w_ˈɒ_n_h_ˈʌ_n_d_ɹ_ə_d_ə_n t_ˈɛ_n ɡ_ˈa_m_ə]\
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An enzyme that catalyzes the conversion of phosphatidylinositol to phosphatidylinositol 3-phosphate. This is the first committed step in the biosynthesis of phosphatidylinositol 3,4-bisphosphate and phosphatidylinositol 3,4,5-trisphosphate. This pathway is thought to play a critical role in DNA repair, V (D)J recombination and cell cycle checkpoints. EC 2.7.1.137.
By DataStellar Co., Ltd
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Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
Nearby Words
- phyz
- phænogamous
- pi
- pi 3k
- pi 3k alpha p85 subunit
- PI 3K Isotype p110 gamma
- pi 4 kinase
- pi dikinase pyruvate
- pi glycan
- pi meson
- pi mesons