PEPO (U.S.)
\pˈiːpə͡ʊ jˌuːˈɛs], \pˈiːpəʊ jˌuːˈɛs], \p_ˈiː_p_əʊ__ j_ˌuː_ˈɛ_s]\
Definitions of PEPO (U.S.)
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Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.