NICCOLO FRANCO

\nɪkˈɒlə͡ʊ fɹˈankə͡ʊ], \nɪkˈɒlə‍ʊ fɹˈankə‍ʊ], \n_ɪ_k_ˈɒ_l_əʊ f_ɹ_ˈa_n_k_əʊ]\
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1910 - Warner's dictionary of authors ancient and modern
By Charles Dudley Warner

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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