MITIGATING CIRCUMSTANCES
\mˈɪtɪɡˌe͡ɪtɪŋ sˈɜːkəmstˌansɪz], \mˈɪtɪɡˌeɪtɪŋ sˈɜːkəmstˌansɪz], \m_ˈɪ_t_ɪ_ɡ_ˌeɪ_t_ɪ_ŋ s_ˈɜː_k_ə_m_s_t_ˌa_n_s_ɪ_z]\
Definitions of MITIGATING CIRCUMSTANCES
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Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.