MARASMIC THROMBOSIS
\maɹˈazmɪk θɹəmbˈə͡ʊsɪs], \maɹˈazmɪk θɹəmbˈəʊsɪs], \m_a_ɹ_ˈa_z_m_ɪ_k θ_ɹ_ə_m_b_ˈəʊ_s_ɪ_s]\
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Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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