HIOB LUDOLF

\hɪˈɒb lˈuːdɒlf], \hɪˈɒb lˈuːdɒlf], \h_ɪ__ˈɒ_b l_ˈuː_d_ɒ_l_f]\
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1910 - Warner's dictionary of authors ancient and modern
By Charles Dudley Warner

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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