GROLIER

\ɡɹˈə͡ʊliə], \ɡɹˈə‍ʊliə], \ɡ_ɹ_ˈəʊ_l_i__ə]\

Definitions of GROLIER

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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