FRIARS HALSAM

\fɹˈa͡ɪ͡əz hˈalsəm], \fɹˈa‍ɪ‍əz hˈalsəm], \f_ɹ_ˈaɪə_z h_ˈa_l_s_ə_m]\

Definitions of FRIARS HALSAM

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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