CHASE'S SIGN

\t͡ʃˈe͡ɪsɪz sˈa͡ɪn], \t‍ʃˈe‍ɪsɪz sˈa‍ɪn], \tʃ_ˈeɪ_s_ɪ_z s_ˈaɪ_n]\

Definitions of CHASE'S SIGN

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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