AMPUDIA, PEDRO DE

\ampjˈuːdi͡ə], \ampjˈuːdi‍ə], \a_m_p_j_ˈuː_d_iə]\

Definitions of AMPUDIA, PEDRO DE

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1894 - Dictionary of United States history
By John Franklin Jameson

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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